Childhood Cancer in Britain

Abstract
Cancer is diagnosed in about 140 per million children in Britain each year. There is a 1 in 500 chance that a child will be affected in the first 15 years of life, the most frequently occurring types of cancer being leukaemia and brain tumours. This book covers the descriptive epidemiology of childhood cancer in Britain through a series of analyses based on data from the National Registry of Childhood Tumours, the largest population-based specialist children's cancer registry in the world. The central four chapters are devoted to detailed analyses of the data. Throughout these chapters, the diagnoses are classified according to the International Classification of Childhood Cancer, Third Edition. First, there is a comprehensive account of national incidence during 1991–2000, with tables of rates and age-incidence graphs for all the major types of childhood cancer. This is followed by an analysis of incidence trends during 1966–2000. The chapter on survival includes a detailed account of survival rates for 1991–2000, analyses of trends during 1966–2000 with a discussion of how they are related to clinical progress, and information on long-term survival. The chapter on mortality gives an account of childhood cancer mortality during 1965–2004. These chapters are preceded by accounts of the history and methodology of the registry, and of the methods used for analyzing the data. The book concludes with a review of past, current and future functions of the registry and uses of its data.