Regulation of extracellular matrix degradation by cell—extracellular matrix interactions
- 1 December 1990
- journal article
- Published by Elsevier BV in Cell Differentiation and Development
- Vol. 32 (3), 299-306
- https://doi.org/10.1016/0922-3371(90)90043-v
Abstract
An appropriate balance of extracellular matrix synthesis and degradation is required for normal morphogenesis and maintenance of tissue architecture. Extracellular matrix molecules and their receptors, as well as proteinases and their inhibitors, are all involved in matrix remodeling. In this report we show that signal transduction through extracellular matrix receptors regulates matrix remodeling.Keywords
This publication has 43 references indexed in Scilit:
- Control of intracellular pH and growth by fibronectin in capillary endothelial cells.The Journal of cell biology, 1990
- The CD2-LFA-3 and LFA-1-ICAM pathways: relevance to T-cell recognitionImmunology Today, 1989
- Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat.The Journal of cell biology, 1989
- Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.The Journal of cell biology, 1989
- Domains of laminin with growth-factor activityCell, 1989
- Cell surface proteoglycan binds mouse mammary epithelial cells to fibronectin and behaves as a receptor for interstitial matrixThe Journal of cell biology, 1988
- Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo.The Journal of Experimental Medicine, 1987
- Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulationCell, 1987
- Integrins: A family of cell surface receptorsCell, 1987
- Commitment to expression of the metalloendopeptidases, collagenase and stromelysin: relationship of inducing events to changes in cytoskeletal architecture.The Journal of cell biology, 1986