The effect of respiratory tract infections on reported asthma symptoms

Abstract

Background: Wheezing and chest tightness is associated with respiratory tract infections. Thus the occurrence of respiratory tract infections may infl uence the prevalence of asthma. Aims: To assess the strength of relation between two main symptoms of asthma and the prevalence of respiratory tract infections in children with and without asthma. Methods: The study population was 3,796 children, four years of age, whose parents had answered a questionnaire on respiratory symptoms and asthma. The prevalence of wheezing and chest tightness in the last 12 months and four weeks was estimated according to the occurrence of respiratory tract infections during the corresponding time periods; 95% confi dence intervals of the prevalence and the statistical signifi cance of the differences in the prevalence by using chi-square test were calculated. Results: The prevalence of wheezing and chest tightness was higher in children who had experienced respiratory tract infections than in those who had not. The prevalence of wheezing was 17.5% among children who had experienced bronchitis and 3.0% among children whom had not ( pppConclusions: These findings have implications for the interpretation of results from epidemiological studies using respiratory symptoms as a health-related outcome of asthma.