Fabrication of a sensor for simultaneous determination of norepinephrine, acetaminophen and tryptophan using a modified carbon nanotube paste electrode
- 1 January 2012
- journal article
- Published by Royal Society of Chemistry (RSC) in Analytical Methods
- Vol. 4 (1), 259-264
- https://doi.org/10.1039/c1ay05503h
Abstract
A carbon paste electrode (CPE) was modified by incorporation of carbon nanotubes and ferrocene (FC) and studied in pH 7.0 phosphate buffer solution (PBS) by cyclic voltammetry (CV). The modified electrode showed an excellent electrocatalytic effect on the oxidation of norepinephrine (NE). In PBS of pH 7.0, the oxidation current increased linearly with concentration of NE from 0.47 to 500.0 μmol L−1. The detection limit (3σ) obtained by differential pulse voltammetry (DPV) was 0.21 μmol L−1. Then the modified electrode was used to determine NE in an excess of acetaminophen (AC) and tryptophan (TRP) by DPV. Finally, this method was used for the determination of NE, AC and TRP in some real samples.Keywords
This publication has 31 references indexed in Scilit:
- Electrocatalytic and simultaneous determination of isoproterenol, uric acid and folic acid at molybdenum (VI) complex-carbon nanotube paste electrodeElectrochimica Acta, 2011
- Application of a Carbon‐Paste Electrode Modified with 2,7‐Bis(ferrocenyl ethyl)fluoren‐9‐one and Carbon Nanotubes for Voltammetric Determination of Levodopa in the Presence of Uric Acid and Folic AcidElectroanalysis, 2011
- N‐(3,4‐Dihydroxyphenethyl)‐3,5‐dinitrobenzamide‐Modified Multiwall Carbon Nanotubes Paste Electrode as a Novel Sensor for Simultaneous Determination of Penicillamine, Uric acid, and TryptophanElectroanalysis, 2011
- Electrocatalytic oxidation and nanomolar detection of hydrazine by luteolin electrodeposited at a multi-walled carbon nanotube and ionic liquid composite modified screen printed carbon electrodeAnalytical Methods, 2010
- Nanomolar detection ofdopamine at multi-walled carbon nanotube grafted silica network/gold nanoparticle functionalised nanocomposite electrodesThe Analyst, 2009
- Electrochemical study and flow injection analysis of paracetamol in pharmaceutical formulations based on screen-printed electrodes and carbon nanotubesAnalytica Chimica Acta, 2009
- Electrochemical determination of acetaminophen using a glassy carbon electrode coated with a single-wall carbon nanotube-dicetyl phosphate filmMicrochimica Acta, 2006
- Carbon paste electrode incorporating multi-walled carbon nanotube/cobalt salophen for sensitive voltammetric determination of tryptophanSensors and Actuators B: Chemical, 2006
- A sensor for acetaminophen in a blood medium using a Cu(II)-conducting polymer complex modified electrodeAnalytica Chimica Acta, 2004
- Acetaminophen inhibits liver tryptophan-2,3-dioxygenase activity with a concomitant rise in brain serotonin levels and a reduction in urinary 5-hydroxyindole acetic acidLife Sciences, 2000