Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation
Open Access
- 1 February 2009
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 284 (6), 3917-3924
- https://doi.org/10.1074/jbc.m806312200
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- Structural basis for distinctive recognition of fibrinogen γC peptide by the platelet integrin αIIbβ3The Journal of cell biology, 2008
- High-resolution structure prediction and the crystallographic phase problemNature, 2007
- Requirement of α and β subunit transmembrane helix separation for integrin outside-in signalingBlood, 2007
- Structural Basis of Integrin Regulation and SignalingAnnual Review of Immunology, 2007
- Integrin structures and conformational signalingCurrent Opinion in Cell Biology, 2006
- Allosteric β1 Integrin Antibodies That Stabilize the Low Affinity State by Preventing the Swing-out of the Hybrid DomainPublished by Elsevier BV ,2004
- Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studiesBiochemical Journal, 2003
- Conformational Changes in the Integrin औA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain MovementJournal of Biological Chemistry, 2003
- Crystal Structure of the Extracellular Segment of Integrin αVβ3Science, 2001
- Deviations from Standard Atomic Volumes as a Quality Measure for Protein Crystal StructuresJournal of Molecular Biology, 1996