Similar Amino Acid Sequences: Chance or Common Ancestry?
- 9 October 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 214 (4517), 149-159
- https://doi.org/10.1126/science.7280687
Abstract
The systemic comparison of every newly determined amino acid sequence with all other known sequences may allow a complete reconstruction of the evolutionary events leading to contemporary proteins. But sometimes the surviving similarities are so vague that even computer-based sequence comparisons procedures are unable to validate relationships. In other cases similar sequences may appear in totally alien proteins as a result of mere chance or, occasionally, by the convergent evolution of sequences with special properties.Keywords
This publication has 80 references indexed in Scilit:
- Analysis of the nucleotide sequence of an invertible controlling element.Proceedings of the National Academy of Sciences, 1980
- A surprising new protein superfamily containing ovalbumin, antithrombin-III, and alpha1-proteinase inhibitorBiochemical and Biophysical Research Communications, 1980
- The “cytochrome b5 fold”: Structure of a novel protein superfamilyJournal of Molecular Biology, 1979
- COMPLETE AMINO ACID SEQUENCE OF A NEW TYPE OF CARDIOTOXIN OF BUNGARUS FASCIATUS VENOMInternational Journal of Peptide and Protein Research, 1978
- Predicted structure for aldolaseJournal of Molecular Biology, 1976
- Inorganic types of fermentation and anaerobic respirations in the evolution of energy-yielding metabolismOrigins of Life, 1974
- Homology of myosin light chains, troponin-C and parvalbumins deduced from comparison of their amino acid sequencesBiochemical and Biophysical Research Communications, 1974
- An evaluation of the relatedness of proteins based on comparison of amino acid sequencesJournal of Molecular Biology, 1970
- Regulation of chromosome replication in Escherichia coli: a comparison of the effects of phenethyl alcohol treatment with those of amino acid starvationJournal of Molecular Biology, 1966
- An improved method of testing for evolutionary homologyJournal of Molecular Biology, 1966