Convenient Routes to Substituted Benzimidazoles and Imidazolo[4,5-b]pyridines Using Nitrobenzene as Oxidant
- 1 April 1990
- journal article
- research article
- Published by Informa UK Limited in Synthetic Communications
- Vol. 20 (7), 955-963
- https://doi.org/10.1080/00397919008052798
Abstract
Various substituted benzimidazoles and imidazolo[4,5-b] pyridines 5a-c have been prepared by condensation of appropriate diamines and aldehydes in nitrobenzene. This method has been utilized to synthesize compounds 5f-h, which are analogues of the DNA binding fluorochrome Hoechst 33258.Keywords
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