Propofol induces proliferation and invasion of gallbladder cancer cells through activation of Nrf2
Open Access
- 19 August 2012
- journal article
- Published by Springer Science and Business Media LLC in Journal of Experimental & Clinical Cancer Research
- Vol. 31 (1), 66-8
- https://doi.org/10.1186/1756-9966-31-66
Abstract
Propofol is one of the most commonly used intravenous anaesthetic agents during cancer resection surgery, but the effect of propofol on gallbladder cancer is not clear. NF-E2-related factor 2 (Nrf2) is abundantly expressed in cancer cells and relates to proliferation, invasion, and chemoresistance. The aims of the current study were to evaluate effects of propofol on the behavior of human GC cells and role of Nrf2 in these effects.Keywords
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