Multiplex PCR Method for Identifying Recombinant Vaccine-Related Polioviruses
Open Access
- 1 September 2004
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 42 (9), 4313-4315
- https://doi.org/10.1128/jcm.42.9.4313-4315.2004
Abstract
The recent discovery of recombinant circulating vaccine-derived poliovirus (recombinant cVDPV) has highlighted the need for enhanced global poliovirus surveillance to assure timely detection of any future cVDPV outbreaks. Six pairs of Sabin strain-specific recombinant primers were designed to permit rapid screening for VDPV recombinants by PCR.Keywords
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