Transformation of Folate-Consuming Lactobacillus gasseri into a Folate Producer
Open Access
- 1 May 2004
- journal article
- research article
- Published by American Society for Microbiology in Applied and Environmental Microbiology
- Vol. 70 (5), 3146-3148
- https://doi.org/10.1128/aem.70.5.3146-3148.2004
Abstract
Five genes essential for folate biosynthesis in Lactococcus lactis were cloned on a broad-host-range lactococcal vector and were transferred to the folate auxotroph Lactobacillus gasseri . As a result L. gasseri changed from a folate consumer to a folate producer. This principle can be used to increase folate levels in many fermented food products.Keywords
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