Muscle Weakness and Falls in Older Adults: A Systematic Review and Meta‐Analysis
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- 15 June 2004
- journal article
- research article
- Published by Wiley in Journal of the American Geriatrics Society
- Vol. 52 (7), 1121-1129
- https://doi.org/10.1111/j.1532-5415.2004.52310.x
Abstract
To evaluate and summarize the evidence of muscle weakness as a risk factor for falls in older adults. Random-effects meta-analysis. English-language studies indexed in MEDLINE and CINAHL (1985-2002) under the key words aged and accidental falls and risk factors; bibliographies of retrieved papers. Fifty percent or more subjects in a study were aged 65 and older. Studies of institutionalized and community-dwelling subjects were included. Prospective cohort studies that included measurement of muscle strength at inception (in isolation or with other factors) with follow-up for occurrence of falls. Sample size, population, setting, measure of muscle strength, and length of follow-up, raw data if no risk estimate, odds ratios (ORs), rate ratios, or incidence density ratios. Each study was assessed using the validity criteria: adjustment for confounders, objective definition of fall outcome, reliable method of measuring muscle strength, and blinded outcome measurement. Thirty studies met the selection criteria; data were available from 13. For lower extremity weakness, the combined OR was 1.76 (95% confidence interval (CI)=1.31-2.37) for any fall and 3.06 (95% CI=1.86-5.04) for recurrent falls. For upper extremity weakness the combined OR was 1.53 (95% CI=1.01-2.32) for any fall and 1.41 (95% CI=1.25-1.59) for recurrent falls. Muscle strength (especially lower extremity) should be one of the factors that is assessed and treated in older adults at risk for falls. More clinical trials are needed to isolate whether muscle-strengthening exercises are effective in preventing falls.Keywords
This publication has 51 references indexed in Scilit:
- Soft tissue injury resulting from falling predicts a future major falling injury in the home dwelling elderlyJournal of Epidemiology and Community Health, 2000
- Reproducibility of Performance-Based and Self-Reported Measures of Functional StatusThe Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 1997
- Clinical and Biomechanical Measures of Balance Fall Predictors in Ambulatory Nursing Home ResidentsThe Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 1996
- Prevention of falls in the elderlyBone, 1996
- Muscle Performance and Structure in the Elderly as Studied Cross-sectionally and LongitudinallyThe Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 1995
- Strength Is a Major Factor in Balance, Gait, and the Occurrence of FallsThe Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 1995
- Predictors for recurrent falls among the home-dwelling elderlyScandinavian Journal of Primary Health Care, 1995
- Clinical Parameters Associated with Falls in an Elderly PopulationGerontology, 1993
- Examination by logistic regression modelling of the variables which increase the relative risk of elderly women falling compared to elderly menJournal of Clinical Epidemiology, 1990
- Risk Factors for Falls among Elderly Persons Living in the CommunityThe New England Journal of Medicine, 1988