Psychopathology and treatment of 30,344 twins in Sweden. II. Heritability estimates of psychiatric diagnosis and treatment in 12,884 twin pairs
- 1 January 1991
- journal article
- Published by Wiley in Acta Psychiatrica Scandinavica
- Vol. 83 (1), 12-15
- https://doi.org/10.1111/j.1600-0447.1991.tb05504.x
Abstract
We estimated the heritability for inpatient psychiatric treatment, treatment with psychoactive medication, and for psychiatric diagnoses in a randomized sample of 12,884 Swedish twin pairs drawn from the general population for a health survey. We found a genetic contribution to treatment and diagnosis, independent of sex and shared environment. The heritability estimate for inpatient treatment was 0.47, for reported treatment with psychoactive medication 0.49, and for an inpatient diagnosis of neurotic or personality disorder 0.60. No statistically significant heritability was found for the diagnoses of alcohol abuse nor for the heterogeneous group of diagnoses of psychoses. This was probably because of the heterogeneity of cases necessary to form large enough groups for analysis, or ascertainment requiring treatment in a psychiatric unit.Keywords
This publication has 22 references indexed in Scilit:
- The genetics of six neurotic disorders: a twin studyJournal of Affective Disorders, 1990
- Allelic association of human dopamine D2 receptor gene in alcoholismJAMA, 1990
- The Role of Inheritance in BehaviorScience, 1990
- Determining zygosity in the Vietnam Era Twin Registry: an approach using questionnairesClinical Genetics, 1989
- Twin Birth and Adult Psychiatric DisorderThe British Journal of Psychiatry, 1988
- Neuroticism, extraversion, and related traits in adult twins reared apart and reared together.Journal of Personality and Social Psychology, 1988
- Neuroticism, extraversion, and related traits in adult twins reared apart and reared together.Journal of Personality and Social Psychology, 1988
- The genetics of alcoholisms and related disordersJournal of Psychiatric Research, 1987
- Pharmacogenetics of psychoactive drugsJournal of Psychiatric Research, 1987
- Assessment of heritability for personality, based on a short-form of the Eysenck personality inventory: A study of 12,898 twin pairsBehavior Genetics, 1980