Myocardial adaptations in the failing heart: cause or consequence?
- 1 December 2008
- journal article
- review article
- Published by Springer Science and Business Media LLC in Journal of Muscle Research and Cell Motility
- Vol. 29 (6-8), 159-162
- https://doi.org/10.1007/s10974-009-9169-x
Abstract
Many changes in morphology, biochemical properties and myocyte function occur during development to heart failure. Most changes may be compensatory, yet unable to prevent cardiac dysfunction in the long run. This illustrates that it is important to carefully dissect the disease causing modifications from cardiac adaptation, in order to obtain a better understanding of the pathophysiological processes leading to heart failure.Keywords
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