Archaeosomes based on synthetic tetraether-like lipids as novel versatile gene delivery systems
- 11 April 2007
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 20,p. 2054-2056
- https://doi.org/10.1039/b618568a
Abstract
Novel cationic liposomes, termed “archaeosomes”, based on mixtures of neutral/cationic bilayer-forming lipids and archaeobacterial synthetic tetraether-type bipolar lipids show efficient in vitro gene transfection properties and represent a new approach for modulating the lipidic membrane fluidity of the complexes they form with DNA.Keywords
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