Very Early Mobilisation and Complications in the First 3 Months after Stroke: Further Results from Phase II of A Very Early Rehabilitation Trial (AVERT)
- 30 July 2009
- journal article
- research article
- Published by S. Karger AG in Cerebrovascular Diseases
- Vol. 28 (4), 378-383
- https://doi.org/10.1159/000230712
Abstract
Background: Interventions that may reduce the number and severity of potentially harmful post-stroke complications are desirable. This study explored whether very early and frequent mobilisation (VEM) affected complication type (immobility/stroke related), number and severity. Methods: Secondary analysis from phase II, randomised controlled trial. Patients admitted within 24 h of stroke, whose physiological parameters fell within set limits, were randomised to either VEM, commencing <24 h, or standard care. Complications to 3 months were recorded by a blinded assessor and classified by a neurologist. Analysis was intention to treat. Results: Seventy-one patients were recruited (standard care 33; VEM 38).There were no significant group differences in the number, type or severity of complications by 3 months, and most patients (81.6%) experienced one or more complications. Falls were common, while depression was absent. The multivariate analysis showed older age (OR 1.10, 95% CI: 1.02–1.18, p = 0.009) and longer length of stay (OR 1.18, 95% CI: 1.06–1.32, p = 0.002) were associated with experiencing an immobility-related complication. Conclusion: Interventions that promote recovery and reduce complications may consequently reduce length of stay. The larger phase III trial currently underway may shed light on whether increasing mobilisation reduces complications after stroke.This publication has 10 references indexed in Scilit:
- The effect of very early mobilisation after stroke on psychological well-beingJournal of Rehabilitation Medicine, 2008
- Medical Complications in a Comprehensive Stroke Unit and an Early Supported Discharge ServiceStroke, 2008
- A Very Early Rehabilitation Trial for Stroke (AVERT)Stroke, 2008
- Organised inpatient (stroke unit) care for strokePublished by Wiley ,2007
- Exercise for acutely hospitalised older medical patientsPublished by Wiley ,2006
- Frequency of Depression After StrokeStroke, 2005
- Inactive and AloneStroke, 2004
- Hazards of Hospitalization of the ElderlyAnnals of Internal Medicine, 1993
- The frequency, causes and timing of death within 30 days of a first stroke: the Oxfordshire Community Stroke Project.Journal of Neurology, Neurosurgery & Psychiatry, 1990
- Measurements of acute cerebral infarction: a clinical examination scale.Stroke, 1989