The effect of neural adaptation on population coding accuracy
- 14 September 2011
- journal article
- research article
- Published by Springer Science and Business Media LLC in Journal of Computational Neuroscience
- Vol. 32 (3), 387-402
- https://doi.org/10.1007/s10827-011-0358-4
Abstract
Most neurons in the primary visual cortex initially respond vigorously when a preferred stimulus is presented, but adapt as stimulation continues. The functional consequences of adaptation are unclear. Typically a reduction of firing rate would reduce single neuron accuracy as less spikes are available for decoding, but it has been suggested that on the population level, adaptation increases coding accuracy. This question requires careful analysis as adaptation not only changes the firing rates of neurons, but also the neural variability and correlations between neurons, which affect coding accuracy as well. We calculate the coding accuracy using a computational model that implements two forms of adaptation: spike frequency adaptation and synaptic adaptation in the form of short-term synaptic plasticity. We find that the net effect of adaptation is subtle and heterogeneous. Depending on adaptation mechanism and test stimulus, adaptation can either increase or decrease coding accuracy. We discuss the neurophysiological and psychophysical implications of the findings and relate it to published experimental data.Keywords
This publication has 60 references indexed in Scilit:
- Is the Homunculus “Aware” of Sensory Adaptation?Neural Computation, 2009
- Perceptual organization in the tilt illusionJournal of Vision, 2009
- Spatial and Temporal Scales of Neuronal Correlation in Primary Visual CortexJournal of Neuroscience, 2008
- Visual Cells Remember Earlier Applied Target: Plasticity of Orientation SelectivityPLOS ONE, 2008
- Can attractor network models account for the statistics of firing during persistent activity in prefrontal cortex?Frontiers in Neuroscience, 2008
- Synchrony between orientation-selective neurons is modulated during adaptation-induced plasticity in cat visual cortexBMC Neuroscience, 2008
- Sensory adaptationCurrent Opinion in Neurobiology, 2007
- Short-Term Depression in Thalamocortical Synapses of Cat Primary Visual CortexJournal of Neuroscience, 2005
- Coordinate Synaptic Mechanisms Contributing to Olfactory Cortical AdaptationJournal of Neuroscience, 2004
- Spatial and temporal coherence in cortico-cortical connections: A cross-correlation study in areas 17 and 18 in the catVisual Neuroscience, 1992