Longitudinal monitoring of EGFR mutations in plasma predicts outcomes of NSCLC patients treated with EGFR TKIs: Korean Lung Cancer Consortium (KLCC-12-02)

Abstract

// <![CDATA[ $('.header-date').hide();$('#titleAuthors').hide();$('#abstractHeader').hide(); // ]]> Ji Yun Lee1,*, Xu Qing2,*, Wei Xiumin2, Bai Yali2, Sangah Chi3, So Hyeon Bak4, Ho Yun Lee5, Jong-Mu Sun1, Se-Hoon Lee1, Jin Seok Ahn1, Eun Kyung Cho6, Dong-Wan Kim7, Hye Ryun Kim8, Young Joo Min9, Sin-Ho Jung3, Keunchil Park1, Mao Mao2 and Myung-Ju Ahn1 1 Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 2 Translational Bioscience and Diagnostics, WuXi AppTec, Waigaoqiao Free Trade Zone, Shanghai, China 3 Department of Biostatistics and Bioinformatics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 4 Department of Radiology, Kangwon National University Hospital, Chuncheon, Korea 5 Department of Radiology, Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 6 Division of Hematology-Oncology, Department of Medicine, Gachon Medical School, Gil Medical Center, Inchon, Korea 7 Division of Hematology-Oncology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea 8 Division of Oncology, Department of Medicine, Yonsei University College of Medicine, Seoul, Korea 9 Department of Oncology, Asan Medical Center, University of Ulsan college of Medicine, Seoul, Korea * These authors have contributed equally to this study Correspondence to: Myung-Ju Ahn, email: // <![CDATA[ mail("silk.ahn","samsung",0,"") // ]]> Mao Mao, email: // <![CDATA[ mail("mao_m","yahoo",0,"") // ]]> Keywords: NSCLC, EGFR, TKI treatment, droplet digital PCR, liquid biopsy Received: August 31, 2015 Accepted: January 03, 2016 Published: January 09, 2016