Design and synthesis of alkyl 7,7-dihalo-3-methyl-5-(nitrophenyl)-2-azabicyclo[4.1.0]hept-3-ene-4-carboxylates with calcium channel antagonist activity
- 2 June 2005
- journal article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry
- Vol. 13 (12), 4085-4091
- https://doi.org/10.1016/j.bmc.2005.03.047
Abstract
No abstract availableKeywords
This publication has 36 references indexed in Scilit:
- Synthesis, Rotamer Orientation, and Calcium Channel Modulation Activities of Alkyl and 2-Phenethyl 1,4-Dihydro-2,6-dimethyl-3-nitro-4-(3- or 6-substituted-2-pyridyl)-5-pyridinecarboxylatesJournal of Medicinal Chemistry, 1998
- A molecular graphics study on structure-action relationships of calcium-antagonistic and agonistic 1,4-dihydropyridinesJournal of Computer-Aided Molecular Design, 1987
- Calcium-entry blockers and cardiovascular diseaseThe American Journal of Cardiology, 1983
- New developments in calcium ion channel antagonistsJournal of Medicinal Chemistry, 1983
- Novel dihydropyridines with positive inotropic action through activation of Ca2+ channelsNature, 1983
- The Properties and Reactivity of Methylene: Derived Principally from its Gas‐Phase ReactionsProgress in Physical Organic Chemistry, 1964
- Methylene, CH2. Stereospecific Reaction with cis- and trans-2-ButeneJournal of the American Chemical Society, 1959
- The Electron-seeking Demands of Dichlorocarbene in its Addition to OlefinsJournal of the American Chemical Society, 1958
- Reactions of Bivalent Carbon Compounds. Reactivities in Olefin-Dibromocarbene ReactionsJournal of the American Chemical Society, 1956
- Syntheses in the Indene Series1Journal of the American Chemical Society, 1953