Myopericytoma of the lip: Report of case

Abstract

Background. Myopericytoma is a recently delineated entity showing a hemangiopericytoma‐like vascular pattern. This rare mesenchymal neoplasm arises within the subcutaneous tissue of the extremities. Only 3 cases of myopericytoma involving the soft tissues of the mouth have been reported, and this case is the first, to the best of our knowledge, that involves the lips. Methods. A 28‐year‐old black man had a slowly growing, painless, firm, ulcerated lower lip mass. Histopathologic examination and immunohistochemical analysis were performed, and the differential diagnosis included carcinoma and other well‐circumscribed, vascular, slow‐growing lesions of the mouth‐like myofibroma, glomus tumor, and solitary fibrous tumor. Results. The results of the histology combined with the immunohistochemical analysis led to a diagnosis of myopericytoma. Conclusions. This case may aid others in recognizing this very rare entity. As the myopericytoma shares morphologic features with other perivascular myoid neoplasms, it should be included in the differential diagnosis of well‐circumscribed, vascular, slow‐growing lesions of the mouth. © 2008 Wiley Periodicals, Inc. Head Neck, 2009