Occupation and cancer in Britain
Open Access
- 27 April 2010
- journal article
- Published by Springer Science and Business Media LLC in British Journal of Cancer
- Vol. 102 (9), 1428-1437
- https://doi.org/10.1038/sj.bjc.6605637
Abstract
Prioritising control measures for occupationally related cancers should be evidence based. We estimated the current burden of cancer in Britain attributable to past occupational exposures for International Agency for Research on Cancer (IARC) group 1 (established) and 2A (probable) carcinogens. We calculated attributable fractions and numbers for cancer mortality and incidence using risk estimates from the literature and national data sources to estimate proportions exposed. 5.3% (8019) cancer deaths were attributable to occupation in 2005 (men, 8.2% (6362); women, 2.3% (1657)). Attributable incidence estimates are 13 679 (4.0%) cancer registrations (men, 10 063 (5.7%); women, 3616 (2.2%)). Occupational attributable fractions are over 2% for mesothelioma, sinonasal, lung, nasopharynx, breast, non-melanoma skin cancer, bladder, oesophagus, soft tissue sarcoma, larynx and stomach cancers. Asbestos, shift work, mineral oils, solar radiation, silica, diesel engine exhaust, coal tars and pitches, occupation as a painter or welder, dioxins, environmental tobacco smoke, radon, tetrachloroethylene, arsenic and strong inorganic mists each contribute 100 or more registrations. Industries and occupations with high cancer registrations include construction, metal working, personal and household services, mining, land transport, printing/publishing, retail/hotels/restaurants, public administration/defence, farming and several manufacturing sectors. 56% of cancer registrations in men are attributable to work in the construction industry (mainly mesotheliomas, lung, stomach, bladder and non-melanoma skin cancers) and 54% of cancer registrations in women are attributable to shift work (breast cancer). This project is the first to quantify in detail the burden of cancer and mortality due to occupation specifically for Britain. It highlights the impact of occupational exposures, together with the occupational circumstances and industrial areas where exposures to carcinogenic agents occurred in the past, on population cancer morbidity and mortality; this can be compared with the impact of other causes of cancer. Risk reduction strategies should focus on those workplaces where such exposures are still occurring.Keywords
This publication has 33 references indexed in Scilit:
- Occupational exposure to diesel engine exhaust: A literature reviewJournal of Exposure Science & Environmental Epidemiology, 2009
- Occupational, domestic and environmental mesothelioma risks in the British population: a case–control studyBritish Journal of Cancer, 2009
- The burden of cancer at work: estimation as the first step to preventionOccupational and Environmental Medicine, 2008
- Epidemiology of nonmelanoma skin cancer (NMSC) in Europe: accurate and comparable data are needed for effective public health monitoring and interventionsBritish Journal of Dermatology, 2007
- The global burden of disease due to occupational carcinogensAmerican Journal of Industrial Medicine, 2005
- Estimating the Number of Asbestos-related Lung Cancer Deaths in Great Britain from 1980 to 2000Annals of Occupational Hygiene, 2005
- Job tenure in Britain, 1975–2000. Is a job for life or just for Christmas?*Oxford Bulletin of Economics and Statistics, 2002
- Respirable Dust and Respirable Silica Concentrations from Construction ActivitiesIndoor and Built Environment, 1999
- Malignant mesothelioma in south east England: clinicopathological experience of 272 cases [published erratum appears in Thorax 1997 Nov;52(11):1018]Thorax, 1997
- Malignant mesothelioma: attributable risk of asbestos exposure.Occupational and Environmental Medicine, 1994