Anticlotting properties of fragments D from human fibrinogen and fibrin
- 1 August 1979
- journal article
- Published by Wiley in European Journal of Clinical Investigation
- Vol. 9 (4), 253-255
- https://doi.org/10.1111/j.1365-2362.1979.tb00881.x
Abstract
It appeared from our previous studies that Ca2+ concentrations comparable to those occurring in blood protect the C-terminal part of the gamma-chain remnants of fibrin(ogen) fragments D against further plasmin attack. This study shows that purified fibrin(ogen) fragments D formed in the presence of Ca2+ ions have anticlotting activity in vitro, whereas shortening of the gamma-chain remnants leads to loss of such activity.Keywords
This publication has 12 references indexed in Scilit:
- Calcium‐binding properties of human fibrin(ogen) and degradation productsFEBS Letters, 1979
- Ca binding of rat fibrinogen and fibrin(ogen) degradation productsFEBS Letters, 1978
- Purification of rat fibrinogen and its constituent chainsBiochemical Journal, 1978
- Protective effect of calcium in the plasmin degradation of fibrinogen and fibrin fragments DThrombosis Research, 1977
- Fragments D - correlation between structure and biological activityThrombosis Research, 1977
- Fibrinogen, Fibrinogen Degradation Products and Erythrocyte FlexibilityThrombosis and Haemostasis, 1977
- [23] Rabbit plasminogen and plasmin isozymesMethods in enzymology, 1976
- [48] PlasminogenMethods in enzymology, 1974
- PATHOGENESIS OF THE COAGULATION DEFECT DEVELOPING DURING PATHOLOGICAL PLASMA PROTEOLYTIC (“FIBRINOLYTIC”) STATES. II. THE SIGNIFICANCE, MECHANISM AND CONSEQUENCES OF DEFECTIVE FIBRIN POLYMERIZATION*JCI Insight, 1962
- ANTICOAGULANT EFFECT OF INCUBATED FIBRINOGENCanadian Journal of Biochemistry and Physiology, 1958