The FAF-Drugs2 server: a multistep engine to prepare electronic chemical compound collections
Open Access
- 2 June 2011
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 27 (14), 2018-2020
- https://doi.org/10.1093/bioinformatics/btr333
Abstract
Summary:The FAF-Drugs2 server is a web application that prepares chemical compound libraries prior to virtual screening or that assists hit selection/lead optimization before chemical synthesis or ordering. The FAF-Drugs2 web server is an enhanced version of the FAF-Drugs2 package that now includes Pan Assay Interference Compounds detection. This online toolkit has been designed through a user-centered approach with emphasis on user-friendliness. This is a unique online tool allowing to prepare large compound libraries with in house or user-defined filtering parameters. Availability: The FAF-Drugs2 server is freely available at http://bioserv.rpbs.univ-paris-diderot.fr/FAF-Drugs/. Contact:david.lagorce@inserm.fr; bruno.villoutreix@inserm.fr Supplementary information: Supplementary data are available at Bioinformatics online.Keywords
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