Considerations for Prognosis, Goals of Care, and Specialty Palliative Care for Hospitalized Patients With Acute‐on‐Chronic Liver Failure

Abstract

Acute‐on‐chronic liver failure (ACLF) occurs in about 25% of hospitalized patients with decompensated cirrhosis (DC) (1) and is associated with high, short‐term mortality (1, 2). The European Association for the Study of the Liver (EASL) – Chronic Liver Failure (CLIF) EASL‐CLIF Acute‐on‐Chronic Liver Failure in Cirrhosis (CANONIC) study showed that 28‐day mortality could be predicted after the 3^rd day in the intensive care unit (ICU) applying the CLIF‐sequential organ failure assessment (SOFA) score (3).