The reaction between thiols and 8-azidoadenosine derivatives
- 1 September 1976
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 3 (9), 2331-2340
- https://doi.org/10.1093/nar/3.9.2331
Abstract
Thiols react at room temperature in dilute solution with 8-azidoadenosine and its nucleotides to give the corresponding 8-aminoadenosine derivatives. The reaction which takes place in the dark is base-catalysed and is particularly rapid when dithiols, e.g. dithiothreitol are used.Keywords
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