Evaluation of the WHO criteria for 75 g oral glucose tolerance test in pregnancy
- 1 September 1987
- journal article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 94 (9), 847-850
- https://doi.org/10.1111/j.1471-0528.1987.tb03752.x
Abstract
A group of pregnant women at high risk of developing diabetes in pregnancy had paired oral glucose tolerance tests (OGTT) using a 100 g load followed by 75 g load. When the World Health Organization (WHO) criteria and the National Diabetes Data Group (NDDG) criteria were compared, the 2-h plasma glucose value after the 100 g load was the most discriminative in differentiating those with normal glucose tolerance, impaired glucose tolerance and gestational diabetes mellitus. When only the 2-h plasma glucose values were assessed, the WHO test (75 g: 8 mmol/l) agreed with the NDDG test (100 g load: 9.2 mmol/l) in the diagnosis of glucose intolerance in 60% of subjects only. Using the same criteria at 2-h (8 mmol/l) the agreement between these tests was 47%. Reducing the glucose load from 100 g to 75 g produced a reduced glucose response in 49% of the subjects, with a significant decrease in the area under the glucose response curve.This publication has 5 references indexed in Scilit:
- Geographic, Ethnic, and Racial Variations in the Incidence of Gestational Diabetes MellitusDiabetes, 1985
- Summary and Recommendations of the Second International Workshop-Conference on Gestational Diabetes MellitusDiabetes, 1985
- Oral Glucose Tolerance Test in PregnancyActa Obstetricia et Gynecologica Scandinavica, 1984
- Classification and Diagnosis of Diabetes Mellitus and Other Categories of Glucose IntoleranceDiabetes, 1979
- Plasma Insulin and Glucose Responses of Healthy Subjects to Varying Glucose Loads During Three-hour Oral Glucose Tolerance TestsDiabetes, 1970