Assay of fluconazole by megabore capillary gas-liquid chromatography with nitrogen-selective detection
- 1 May 1989
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 33 (5), 714-716
- https://doi.org/10.1128/aac.33.5.714
Abstract
A megabore column gas-liquid chromatographic method which uses nitrogen-phosphorus detection was developed for the analysis of fluconazole in plasma, serum, cerebrospinal fluid, or urine. The assay was linear from 0.2 to 200 micrograms/ml and had an average coefficient of variation of 7%. The suitability of the assay for pharmacokinetic studies was demonstrated.This publication has 27 references indexed in Scilit:
- Effect of Antineoplastic Agents on the Growth and Ultrastructure of Candida AlbicansMycoses, 2009
- Determination of Fluconazole in Biological Fluids by Capillary Column Gas Chromatography with a Nitrogen DetectorJournal of Pharmaceutical Sciences, 1988
- Fluconazole Penetration into Cerebrospinal Fluid: Implications for Treating Fungal Infections of the Central Nervous SystemThe Journal of Infectious Diseases, 1988
- Interactions among amphotericin B, 5-fluorocytosine, ketoconazole, and miconazole against pathogenic fungi in vitroAntimicrobial Agents and Chemotherapy, 1982
- Antifungal Action of Amphotericin B in Combination with Other Polyene or Imidazole AntibioticsThe Journal of Infectious Diseases, 1982
- Laboratory evaluation of antifungal agents: a comparative study of five imidazole derivatives of clinical importanceJournal of Antimicrobial Chemotherapy, 1980
- In vitro synergy and antagonism of antifungal agents against yeast-like fungiPublished by Oxford University Press (OUP) ,1979
- Combined Activity of Minocycline and Amphotericin B In Vitro Against Medically Important YeastsAntimicrobial Agents and Chemotherapy, 1978
- A Method for Testing for Synergy with Any Number of AgentsThe Journal of Infectious Diseases, 1978
- Obfuscation of the Activity of Antifungal Antimicrobics by Culture MediaThe Journal of Infectious Diseases, 1972