Cytostatic Intravesical Instillation in Patients with Superficial Bladder Carcinoma for the Prevention of Recurrent Tumors
- 1 January 1988
- journal article
- research article
- Published by Elsevier BV in European Urology
- Vol. 14 (3), 202-206
- https://doi.org/10.1159/000472937
Abstract
The value of various protocols of mitomycin C and adriamycin instillation for the prevention of recurrent tumors in patients whose superficial bladder tumors (TA, T1) had been removed by transurethral resection was compared in a prospective multicenter study. Three-year and short-term instillation protocols were compared with each other and with the combination of the two. Evaluation after a mean follow-up of 20 months confirmed our previous conclusion of the great value of cytostatic bladder instillation to prevent recurrent tumors and tumor progression in patients with superficial bladder carcinoma. There is no significant difference between long-term and short-term prophylaxis, but combination has achieved the best results. Similar results were obtained with adriamycin and mitomycin but adriamycin was less well tolerated.This publication has 3 references indexed in Scilit:
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- The Value of Histologic Grading and Staging, Random Biopsies, Tumor and Bladder Mucosa Blood Group Antigens, in Predicting Progression of Superficial Bladder CancerEuropean Urology, 1984
- Prognostic Parameters in Superficial Bladder Cancer: An Analysis of 315 CasesJournal of Urology, 1982