Distribution Pattern of Computed Tomography Findings in Patients with Bronchiolitis Obliterans Organizing Pneumonia
- 1 May 1996
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Investigative Radiology
- Vol. 31 (5), 251-255
- https://doi.org/10.1097/00004424-199605000-00001
Abstract
RATIONALE AND OBJECTIVES The authors evaluated high-resolution computed tomography (HRCT) findings in 15 patients with biopsy-proven bronchiolitis obliterans organizing pneumonia (BOOP). Special attention was paid to lobar distribution to establish a predominant distribution pattern for this disease. SUBJECTS AND METHODS Fifteen patients (average age, 61.8 years) with BOOP underwent computed tomography examinations. The examination technique included a slice thickness of 4 mm with a 4-mm interval; matrix size was 256 × 256 pixels. In all patients, additional HRCT images with a 2-mm slice thickness and a 10-mm interval (matrix, 512 × 512 pixels) were obtained. Interpretation included assessment of pulmonary, pleural, and mediastinal involvement. Special attention was paid to the distribution pattern of pulmonary abnormalities. RESULTS High-resolution computed tomography in all patients demonstrated areas of air space consolidation in a multifocal but peripheral distribution. The right lower lobe was involved in 60% of the patients, the left lower lobe in 53%, the middle and right upper lobes in 20%, and the left upper lobe in 23%. Five patients had ground-glass opacities in addition to the areas of air space consolidation, with the incidence in these patients being 100% in the right lower lobe, 80% in the left lower and middle lobes, 60% in the right upper lobe, and 20% in the left upper lobe. Nodules were found in two patients, and the left lower and middle lobes were affected in both. In one patient, the right lower lobe was affected. The interstitium was thickened in 66%, with axial involvement in 20%, septal thickening in 30%, and peripheral regions affected in 50%. Bronchiectasis was present in 60% of all patients studied, predominantly located in the lower lobes. CONCLUSION Bronchiolitis obliterans organizing pneumonia presents a predominant peripheral, bilateral, and nonsegmental distribution, with the lower and middle lobes affected more than the upper lobes.Keywords
This publication has 18 references indexed in Scilit:
- Bronchiolitis Obliterans on High-Resolution CTJournal of Computer Assisted Tomography, 1993
- Diagnosis of bronchiolitis obliterans in heart-lung transplantation patients: importance of bronchial dilatation on CT.American Journal of Roentgenology, 1992
- Pathologic aspects of bronchiolitis obliterans organizing pneumoniaSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1992
- Bronchiolitis obliterans organizing pneumonia: definition and clinical featuresSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1992
- Bronchiolitis obliterans after lung transplantation: findings at chest radiography and high-resolution CT. The Toronto Lung Transplant Group.Radiology, 1991
- Bronchiolitis obliterans organizing pneumonia: CT features in 14 patients.American Journal of Roentgenology, 1990
- Bronchiolitis obliterans.Radiology, 1986
- Bronchiolitis Obliterans Organizing PneumoniaNew England Journal of Medicine, 1985
- Fleischner Lecture. Looking into the lung: what can it tell us?American Journal of Roentgenology, 1979
- BRONCHIOLITIS OBLITERANSAmerican Journal of Roentgenology, 1973