Gastrointestinal stromal tumor in a child and review of the literature
- 21 October 2005
- journal article
- case report
- Published by Springer Science and Business Media LLC in Pediatric Surgery International
- Vol. 21 (11), 914-917
- https://doi.org/10.1007/s00383-005-1511-9
Abstract
Gastrointestinal stromal tumors (GIST) are c-KIT positive neoplasm that occur predominantly in adults. A 13-year-old boy who presented with massive gastrointestinal hemorrhage was subsequently diagnosed with GIST of the stomach. The tumor originated from the lesser curvature with a narrow base and no infiltration into surrounding organs. Two metastatic lesions in the liver were also found. Total excision of the gastric lesion was performed followed by adjuvant imatinib mesylate chemotherapy. He has had no signs of recurrence during 8 months of follow-up. GIST in children are rare and their behavior is notoriously difficult to predict. We report our experience and review the literature.Keywords
This publication has 23 references indexed in Scilit:
- Pediatric gastrointestinal stromal tumors and leiomyosarcomaCancer, 2004
- Surgical treatment of gastrointestinal stromal tumors in the imatinib (STI-571) eraSurgery, 2003
- Gastric stromal tumors in childrenPediatric Blood & Cancer, 2003
- Undifferentiated Mesenchymal Neoplasm of the Esophagus in a Child: Case Report and Comparison with Gastrointestinal Stromal TumorPediatric and Developmental Pathology, 2003
- Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal TumorsThe New England Journal of Medicine, 2002
- Epithelioid Gastrointestinal Stromal Tumor of the Stomach with Liver Metastases in a 12-Year-old Girl: Aspiration Cytology and Molecular StudyPediatric and Developmental Pathology, 2002
- Imatinib Mesylate — A New Oral Targeted TherapyThe New England Journal of Medicine, 2002
- The Effect of Surgery and Grade on Outcome of Gastrointestinal Stromal TumorsArchives of Surgery, 2001
- Gastrointestinal Autonomic Nerve Tumor: The youngest case reported in the literatureJournal of Pediatric Gastroenterology and Nutrition, 2000
- Gastrointestinal Autonomic Nerve Tumors A Clinicopathological, Immunohistochemical, and Ultrastructural Study of 12 CasesThe American Journal of Surgical Pathology, 1993