Comment on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity"
Open Access
- 12 January 2007
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 315 (5809), 187
- https://doi.org/10.1126/science.1130571
Abstract
Contrary to the findings of Herbert et al . (Reports, 14 April 2006, p. 279), homozygous carriers of the C allele of the rs7566605 variant near the INSIG2 gene did not exhibit a significantly increased risk for obesity in a large population-based cross-sectional German study. A subgroup analysis, however, revealed that this allele significantly increased the risk for obesity in already overweight individuals.Keywords
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