Capture and Stimulated Release of Circulating Tumor Cells on Polymer‐Grafted Silicon Nanostructures
- 17 December 2012
- journal article
- research article
- Published by Wiley in Advanced Materials
- Vol. 25 (11), 1547-1551
- https://doi.org/10.1002/adma.201203185
Abstract
A platform for capture and release of circulating tumor cells is demonstrated by utilizing polymer grafted silicon nanowires. In this platform, integration of ligand‐receptor recognition, nanostructure amplification, and thermal responsive polymers enables a highly efficient and selective capture of cancer cells. Subsequently, these captured cells are released upon a physical stimulation with outstanding cell viability.Keywords
This publication has 31 references indexed in Scilit:
- Efficient capture of circulating tumor cells with a novel immunocytochemical microfluidic deviceBiomicrofluidics, 2011
- Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic MicromixersAngewandte Chemie-International Edition, 2011
- Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibodyLab on a Chip, 2009
- Three‐Dimensional Nanostructured Substrates toward Efficient Capture of Circulating Tumor CellsAngewandte Chemie-International Edition, 2009
- Biomimetic Nanowire Coatings for Next Generation Adhesive Drug Delivery SystemsNano Letters, 2009
- Highly Efficient Circulating Tumor Cell Isolation from Whole Blood and Label-Free Enumeration Using Polymer-Based Microfluidics with an Integrated Conductivity SensorJournal of the American Chemical Society, 2008
- Isolation of rare circulating tumour cells in cancer patients by microchip technologyNature, 2007
- Cellular and multicellular form and functionAdvanced Drug Delivery Reviews, 2007
- Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast CancerNew England Journal of Medicine, 2004
- Dissecting the metastatic cascadeNature Reviews Cancer, 2004