Chemical and Biological Applications of Digital-Microfluidic Devices
- 29 May 2007
- journal article
- Published by Institute of Electrical and Electronics Engineers (IEEE) in IEEE Design & Test of Computers
- Vol. 24 (1), 10-24
- https://doi.org/10.1109/mdt.2007.8
Abstract
Digital-microfluidic lab-on-a chip (LoC) technology offers a platform for developing diagnostic applications with the advantages of portability, sample and reagent volume reduction, faster analysis, increased automation, low power consumption, compatibility with mass manufacturing, and high throughput. In addition to diagnostics, digital microfluidics is finding use in airborne chemical detection, DNA sequencing by synthesis, and tissue engineering. In this article, we review efforts to develop various LoC applications using electrowetting-based digital microfluidics. We describe these applications, their implementation, and associated design issues.Keywords
This publication has 47 references indexed in Scilit:
- Microparticle sampling by electrowetting-actuated droplet sweepingLab on a Chip, 2005
- Three-Dimensional BioAssembly Tool for Generating Viable Tissue-Engineered ConstructsTissue Engineering, 2004
- Three-Dimensional BioAssembly Tool for Generating Viable Tissue-Engineered ConstructsTissue Engineering, 2004
- Droplet-based microfluidic lab-on-a-chip for glucose detectionAnalytica Chimica Acta, 2004
- Rapid droplet mixers for digital microfluidic systemsLab on a Chip, 2003
- Scaling issues in chemical and biological sensorsProceedings of the IEEE, 2003
- Scaffolds in tissue engineering bone and cartilageBiomaterials, 2000
- Electrowetting-based actuation of liquid droplets for microfluidic applicationsApplied Physics Letters, 2000
- A novel method for nucleic acid sequence determinationJournal of Theoretical Biology, 1988
- Rate and equilibrium studies in Jackson-Meisenheimer complexesChemical Reviews, 1982