Normalization of Genomic DNA Using Duplex-Specific Nuclease

Abstract
An application of duplex-specific nuclease (DSN) normalization technology to whole-genome shotgun sequencing of genomes with a large proportion of repetitive DNA is described. The method uses a thermostable DSN from the ...
Funding Information
  • Evrogen JSC (Russia) and the program “State Support of the Leading Scientific Schools” (NS-2395.2008.4)