Long-term effects of radiation therapy for a catecholamine-producing glomus jugulare tumor
- 1 June 1994
- journal article
- case report
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 80 (6), 1091-1094
- https://doi.org/10.3171/jns.1994.80.6.1091
Abstract
A 42-year-old woman presented with otorrhea 22 years after extracranial resection of a norepinephrine-secreting glomus jugulare tumor with intravascular embolization and radiation therapy to the intracranial portion of the tumor. Tumor growth was arrested and was associated with a decrease in blood and urine norepinephrine levels. Extensive evaluation of the otorrhea, including computerized tomography-cisternography, gadolinium-enhanced magnetic resonance imaging, and arteriography showed marked diffuse necrosis of the temporal bone and skull base with limited tumor vascularity. Cerebrospinal fluid (CSF) collected from the right ear showed norepinephrine levels of 2975 pg/ml; plasma norepinephrine levels were normal. The precise site of CSF leakage could not be delineated. Exploration of the posterior fossa revealed a large dural defect at the anteromedial aspect of the petrous bone through which CSF flowed over the surface of the residual extradural glomus tumor. The defect was successfully sealed with a fascial patch. Postoperatively, CSF norepinephrine levels were normal and no further leakage was observed.Keywords
This publication has 31 references indexed in Scilit:
- Hypothalamic-Pituitary Dysfunction after Radiation for Brain TumorsNew England Journal of Medicine, 1993
- Funktionseinschränkungen der kaudalen Hirnnerven nach Operationen von Tumoren im Foramen jugulareLaryngo-Rhino-Otologie, 1991
- The long-term side effects of radiation therapy for benign brain tumors in adultsJournal of Neurosurgery, 1990
- Radiation therapy for paragangliomas of the temporal boneThe Laryngoscope, 1990
- Radiation or surgery for chemodectoma of the temporal bone: A review of local control and complicationsHead & Neck, 1990
- Effects of preoperative embolization on glomus jugulare tumorsThe Laryngoscope, 1989
- Surgical Management of Glomus TumorsSouthern Medical Journal, 1988
- Diagnosis and management of catecholamine secreting glomus tumors.The Laryngoscope, 1984
- Radionecrosis of the temporal bone.The Laryngoscope, 1966