Initial Interactions of Subgenus D Adenoviruses with A549 Cellular Receptors: Sialic Acid versus α v Integrins
Open Access
- 15 August 2000
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 74 (16), 7691-7693
- https://doi.org/10.1128/jvi.74.16.7691-7693.2000
Abstract
Selected members of the adenovirus family have been shown to interact with the coxsackie adenovirus receptor, α v integrins, and sialic acid on target cells. Initial interactions of subgenus D adenoviruses with target cells have until now been poorly characterized. Here, we demonstrate that adenovirus type 8 (Ad8), Ad19a, and Ad37 use sialic acid as a functional cellular receptor, whereas the Ad9 and Ad19 prototypes do not.Keywords
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