A method was developed to estimate tissue doses from the upper gastrointestinal fluoroscopy examination. It involved measuring the technical parameters of the clinical examination, partitioning the dynamic examination into a set of discrete x-ray fields, and generating corresponding tissue does tables with an existing computer program. Knowledge of the radiation exposures associated with each of the fields enabled the calculation of tissue doses for the entire dynamic examination. In this limited sample (eight patients), fluoroscopy times ranged from 108 to 183 seconds. Radiation exposures ranged from 2.3 to 7.2 mC/kg (9.1-28 R), thyroid doses from 0.15 to 3.5 mGy (15-350 mrad), uterine doses from 0.16 to 1.0 mGy (16-100 mrad), lung doses from 0.90 to 4.2 mGy (90-420 mrad), and active bone marrow doses from 0.81 to 5.4 mGy (81-540 mrad).