Bone Cells in Culture: Morphologic Transformation by Hormones
- 25 June 1976
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 192 (4246), 1340-1343
- https://doi.org/10.1126/science.1273593
Abstract
Hormones and purine nucleosides and nucleotides induced cultured bone cells to transform transiently from a spherical to a stellate shape. Cytochalasin B also induced the transformation. The change was blocked by colchicine and vinblastine, but not by lumicolchicine or cycloheximide. This morphologic transformation may provide a dynamic model of hormone action and bone cell modulation in vitro.Keywords
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