Impact of PANS and PANDAS Exacerbations on Occupational Performance: A Mixed-Methods Study
- 27 March 2017
- journal article
- research article
- Published by AOTA Press in American Journal of Occupational Therapy
- Vol. 71 (3)
- https://doi.org/10.5014/ajot.2017.022285
Abstract
OBJECTIVE. Pediatric acute-onset neuropsychiatric syndrome (PANS) includes pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections and involves sudden-onset neuropsychiatric symptoms, including obsessions, compulsions, sensory difficulties, and dysgraphia after infection or other triggers. Our objective was to identify problems with areas of occupation, body functions, and performance skills during exacerbations. METHOD. In this online retrospective study, based on the Occupational Therapy Practice Framework: Domain and Process (2nd ed.), we surveyed parents of 111 children with PANS. RESULTS. Activities of daily living, math, handwriting, extracurricular activities, free play, organized sports, community and family social participation, higher level thinking, attention, memory, sequencing, emotional coping, and energy and drive were commonly affected during exacerbations. During exacerbations, children often required assistance and adaptation to remain functional or were unable to function at a typical level. CONCLUSION. Children with PANS present with pervasive occupational performance needs during exacerbation. Children and families may benefit from accommodations to maximize function during this turbulent period.Keywords
This publication has 16 references indexed in Scilit:
- Pediatric Acute-Onset Neuropsychiatric SyndromePsychiatric Clinics of North America, 2014
- Occupational Therapy Practice Framework: Domain and Process (3rd Edition)American Journal of Occupational Therapy, 2014
- From Research Subgroup to Clinical Syndrome: Modifying the PANDAS Criteria to Describe PANS (Pediatric Acute-onset Neuropsychiatric Syndrome)Pediatrics & Therapeutics, 2012
- The Immunobiology of Tourette's Disorder, Pediatric Autoimmune Neuropsychiatric Disorders Associated withStreptococcus, and Related Disorders: A Way ForwardJournal of Child and Adolescent Psychopharmacology, 2010
- Comparison of Clinical Characteristics of Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections and Childhood Obsessive-Compulsive DisorderJournal of Child and Adolescent Psychopharmacology, 2010
- Rethinking Mental IllnessJAMA, 2010
- Occupational Therapy Practice Framework: Domain & Process 2nd EditionAmerican Journal of Occupational Therapy, 2008
- Antibody-mediated neuronal cell signaling in behavior and movement disordersJournal of Neuroimmunology, 2006
- Mimicry and autoantibody-mediated neuronal cell signaling in Sydenham choreaNature Medicine, 2003
- Case Study: A New Infection-Triggered, Autoimmune Subtype of Pediatric OCD and Tourette's SyndromeJournal of the American Academy of Child & Adolescent Psychiatry, 1995