The relationship between cellular adhesion and surface roughness for polyurethane modified by microwave plasma radiation
Open Access
- 1 April 2011
- journal article
- research article
- Published by Taylor & Francis Ltd in International Journal of Nanomedicine
- Vol. 6, 641-647
- https://doi.org/10.2147/ijn.s17180
Abstract
Abstract: Surface modification of medical polymers is carried out to improve biocompatibility. In this study, conventional polyurethane was exposed to microwave plasma treatment with oxygen and argon gases for 30 seconds and 60 seconds. Attenuated total reflection Fourier transform infrared spectra investigations of irradiated samples indicated the presence of functional groups. Atomic force microscope images of samples irradiated with inert and active gases indicated the nanometric topography of the sample surfaces. Samples irradiated by oxygen plasma indicated high roughness compared with those irradiated by inert plasma for the different lengths of time. In addition, surface roughness increased with time, which can be due to a reduction of contact angle of samples irradiated by oxygen plasma. Contact angle analysis indicated a reduction in samples irradiated with both types of plasma. However, samples irradiated with oxygen plasma indicated lower contact angle compared with those irradiated by argon plasma. Cellular investigations with unrestricted somatic stem cells showed better adhesion, cell growth, and proliferation among samples radiated by oxygen plasma for longer than for normal samples.Keywords
This publication has 6 references indexed in Scilit:
- Theoretical model for the wetting of a rough surfaceJournal of Colloid and Interface Science, 2008
- Cytokine production and hematopoiesis supporting activity of cord blood–derived unrestricted somatic stem cellsExperimental Hematology, 2005
- In-vitro- und In-vivo-Knochenregenerierung durch mesenchymale Stammzellen aus dem NabelschnurblutDer Orthopäde, 2004
- A New Human Somatic Stem Cell from Placental Cord Blood with Intrinsic Pluripotent Differentiation PotentialThe Journal of Experimental Medicine, 2004
- Hydrophobic mechanochemical treatment of metallic surfaces: Wettability measurements as a means of assessing homogeneityAdvances in Colloid and Interface Science, 2002
- A new peptide-based urethane polymer: synthesis, biodegradation, and potential to support cell growth in vitroBiomaterials, 2000