Stereotactic radiofrequency ablation for the treatment of gelastic seizures associated with hypothalamic hamartoma
- 1 November 1999
- journal article
- case report
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 91 (5), 881-884
- https://doi.org/10.3171/jns.1999.91.5.0881
Abstract
The author presents the case of a patient with gelastic seizures associated with a hypothalamic hamartoma, in whom partial resection of the hamartoma followed by temporal lobectomy and orbitofrontal corticectomy failed to reduce the seizures. Subsequent stereotactic radiofrequency ablation of the hamartoma resulted in progressive improvement in the seizure disorder during a 28-month follow-up period. There is support in the literature for the concept that gelastic seizures originate directly from the hamartoma; however, direct surgical approaches to these lesions pose significant risks. It is proposed that the technique of radiofrequency ablation provides a minimally invasive, low-risk approach for the treatment of hypothalamic hamartomas.Keywords
This publication has 36 references indexed in Scilit:
- Letters to the EditorEpilepsia, 1997
- Intrinsic epileptogenesis of hypothalamic hamartomas in gelastic epilepsyAnnals of Neurology, 1997
- Human Epileptogenesis and Hypothalamic Hamartomas: New Lessons from an Experiment of NatureEpilepsia, 1997
- The running down phenomenon in temporal lobe epilepsyBrain, 1996
- Intrinsic epileptogenicity of human dysplastic cortex as suggested by corticography and surgical resultsAnnals of Neurology, 1995
- Neurosurgical treatment of hypothalamic hamartomas causing precocious pubertyJournal of Neurosurgery, 1993
- Hypothalamic Hamartoma: Report of Two CasesNeurosurgery, 1985
- Hypothalamic hamartomaNeurosurgery, 1985
- Gelastic Epilepsy and True Precocious Puberty due to Hypothalamic HamartomaDevelopmental Medicine and Child Neurology, 1984
- TEMPORAL LOBE EPILEPSY DUE TO DISTANT LESIONS: TWO CASES RELIEVED BY OPERATIONBrain, 1962