Measurement and reporting of the duration of untreated psychosis
- 23 October 2008
- journal article
- research article
- Published by Wiley in Early Intervention in Psychiatry
- Vol. 2 (4), 201-211
- https://doi.org/10.1111/j.1751-7893.2008.00080.x
Abstract
Aim: The aim of this study was to investigate the demographic, illness and methodological factors associated with mean and median duration of untreated psychosis (DUP). Methods: A systematic review and meta‐analysis of the published studies of DUP and an examination of available DUP distributions. Results: DUP was longer in samples with a higher proportion of patients with schizophrenia and was shorter in samples that included affective psychosis. Sex, age, and the methods of measuring the onset and end‐point of DUP and the type of service in which the studies were performed did not contribute to the heterogeneity of the mean or median DUP values. Mean DUP is significantly prolonged by a small number of patients, and the median DUP is a poor indicator of the rate at which patients present. Conclusions: The DUP of patients with affective and non‐affective psychosis should be examined separately in order to make measures of DUP more meaningful and comparable, and DUP should be reported using more comprehensive measures. We suggest a method of reporting DUP based on the rate of presentation of first‐episode psychosis patients rather than the length of DUP.Keywords
This publication has 79 references indexed in Scilit:
- Predictors of acute treatment response in patients with a first episode of non-affective psychosis: Sociodemographics, premorbid and clinical variablesJournal of Psychiatric Research, 2007
- Clinical and demographic features of treated first-episode psychotic disorders: A Zambian studySchizophrenia Research, 2006
- Pattern and Correlates of Inpatient Admission During the Initial Acute Phase of First-Episode PsychosisAustralian & New Zealand Journal of Psychiatry, 2006
- Pretreatment social functioning predicts 1‐year outcome in early onset psychosisActa Psychiatrica Scandinavica, 2006
- Predictors of Psychosis Remission in Psychotic Disorders That Co-occur With Substance UseSchizophrenia Bulletin, 2005
- How should meta‐regression analyses be undertaken and interpreted?Statistics in Medicine, 2002
- The Mexican first-episode psychotic study: clinical characteristics and premorbid adjustmentSchizophrenia Research, 2002
- Shortened Duration of Untreated First Episode of Psychosis: Changes in Patient Characteristics at TreatmentAmerican Journal of Psychiatry, 2001
- The Influence of Age and Sex on the Onset and Early Course of SchizophreniaThe British Journal of Psychiatry, 1993
- The Influence of Ethnicity and Family Structure on Relapse in First-Episode SchizophreniaThe British Journal of Psychiatry, 1992