Mixed glioneuronal tumour of the fourth ventricle with prominent rosette formation
- 22 February 2006
- journal article
- case report
- Published by Wiley in Neuropathology and Applied Neurobiology
- Vol. 32 (2), 217-220
- https://doi.org/10.1111/j.1365-2990.2005.00692.x
Abstract
We describe three unusual tumours characterized by a mixture of glial and neuronal differentiation, involvement of the posterior fossa and formation of rosettes. Mixed glial-neuronal tumours of the posterior fossa are rare and poorly described neoplasms. However, several distinctive entities have appeared in the literature over recent years under a variety of different names. Our cases demonstrate the morphological features of the 'rosette-forming glioneuronal tumour of the fourth ventricle', a recently identified tumour characterised by its unique location, neurocytic pseudo-rosette formation and the presence of a low grade astrocytoma component. The long term prognosis of these tumours remains unclear. However, the clinical data available including the cases presented here, along with the histological features, suggest that these are low grade tumours with a good prognosis after surgical resection.Keywords
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