Standardization ofin vitromethods
- 1 April 2001
- Vol. 56 (s67), 70-74
- https://doi.org/10.1111/j.1398-9995.2001.00921.x
Abstract
IgE‐antibody analysis is a major diagnostic procedure and a primary tool in allergological research. The determination of sensitization frequencies and antibody concentrations against allergens of defined sources provides critical information for the estimation of the relative importance of food and environment in clinical allergy. True quantitation is essential and requires assay designs providing allergen excess and mass unit calibration. Standardized and reproducible methods show geographic and culture dependent differences between patient populations and contribute to the quality of diagnosis and treatment of allergic disease.Keywords
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