Under thermally activated conditions (i.e., temperature of 40∼99°C), there is considerable evidence that the persulfate anion ( ) can be converted to a powerful oxidant known as the sulfate free radical ( ), which could be used in situ to destroy groundwater contaminants. In this laboratory study only limited trichloroethylene (TCE) degradation and no 1,1,1-trichloroethane (TCA) degradation was observed at 20°C. However, TCE and TCA were readily oxidized at 40°, 50°, and 60°C as a result of thermally activated persulfate oxidation. Experiments revealed that the pseudo-first-order reaction rate constants describing contaminant degradation increased with temperature. In aqueous systems activation energies for the TCE and TCA oxidation at an oxidant/contaminant molar ratio of 10/1 were determined to be 97.74±3.04 KJ/mole and 163.86±1.38 KJ/mole at pH 6 and an ionic strength of 0.1, respectively. A significant degradation of TCE and TCA occurs at 40° and 50°C, respectively, within less than 6 h. Aqueous system experiments revealed that oxidation reactions proceed more rapidly at increased persulfate/contaminant molar ratios. Soil slurry tests were conducted using medium to fine sands containing a range of fraction of organic carbon (foc) levels. Soil slurries were prepared at a 1/5 soil/water (mass ratio). In soil slurries the foc exhibited significant competition for sulfate free radicals produced. Based on these results, it was anticipated that higher temperatures, longer treatment times, and higher dosages of persulfate are required for the effective treatment of target contaminants in soil systems vs. aqueous systems.