Convergent recruitment of TALE homeodomain life cycle regulators to direct sporophyte development in land plants and brown algae
Open Access
- 15 January 2019
- journal article
- research article
- Published by eLife Sciences Publications, Ltd in eLife
Abstract
Three amino acid loop extension homeodomain transcription factors (TALE HD TFs) act as life cycle regulators in green algae and land plants. In mosses these regulators are required for the deployment of the sporophyte developmental program. We demonstrate that mutations in either of two TALE HD TF genes, OUROBOROS or SAMSARA, in the brown alga Ectocarpus result in conversion of the sporophyte generation into a gametophyte. The OUROBOROS and SAMSARA proteins heterodimerise in a similar manner to TALE HD TF life cycle regulators in the green lineage. These observations demonstrate that TALE-HD-TF-based life cycle regulation systems have an extremely ancient origin, and that these systems have been independently recruited to regulate sporophyte developmental programs in at least two different complex multicellular eukaryotic supergroups, Archaeplastida and Chromalveolata.Keywords
Funding Information
- Centre National de la Recherche Scientifique
- Agence Nationale de la Recherche (ANR-10-BLAN-1727)
- Interreg program France (Channel)-England (Marinexus)
- University Pierre and Marie Curie
- European Research Council (638240)
- European Commission (European Erasmus Mundus program)
- China Scholarship Council
- Agence Nationale de la Recherche (ANR-10-BTBR-04-01)
- Agence Nationale de la Recherche (ANR-10-LABX-40)
- European Research Council (ERC-SEXYPARTH)
This publication has 55 references indexed in Scilit:
- Scalable web services for the PSIPRED Protein Analysis WorkbenchNucleic Acids Research, 2013
- TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusionsGenome Biology, 2013
- SPINE-D: Accurate Prediction of Short and Long Disordered Regions by a Single Neural-Network Based MethodJournal of Biomolecular Structure and Dynamics, 2012
- GenomeView: a next-generation genome browserNucleic Acids Research, 2011
- OUROBOROS is a master regulator of the gametophyte to sporophyte life cycle transition in the brown alga EctocarpusProceedings of the National Academy of Sciences of the United States of America, 2011
- MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony MethodsMolecular Biology and Evolution, 2011
- The Ectocarpus genome and the independent evolution of multicellularity in brown algaeNature, 2010
- A Comprehensive Classification and Evolutionary Analysis of Plant Homeobox GenesMolecular Biology and Evolution, 2009
- Blast2GO: A Comprehensive Suite for Functional Analysis in Plant GenomicsInternational Journal of Plant Genomics, 2008
- AFLP: a new technique for DNA fingerprintingNucleic Acids Research, 1995