Isolation and structure of the bacterial sex pheromone, cAD1, that induces plasmid transfer in Streptococcus faecalis
- 3 December 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 178 (1), 97-100
- https://doi.org/10.1016/0014-5793(84)81248-x
Abstract
The Streptococcus faecalis sex pheromone cAD1, which is involved in the conjugative transfer of the hemolysin plasmid pAD1, has been isolated and its structure determined. Its M r is 818 and its amino acid sequence is H-Leu-Phe-Ser-Leu-Val-Leu-Ala-Gly-OH. A replicate of the pheromone synthesized by the liquid phase method showed the same biological activity and Chromatographie behavior as the isolated cAD1. Pheromone activity was detectable at a concentration of ~ 5 × 10−11 M.Keywords
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