Diabetic Cardiomyopathy Revisited
Open Access
- 26 June 2007
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 115 (25), 3213-3223
- https://doi.org/10.1161/circulationaha.106.679597
Abstract
Diabetes mellitus increases the risk of heart failure independently of underlying coronary artery disease, and many believe that diabetes leads to cardiomyopathy. The underlying pathogenesis is partially understood. Several factors may contribute to the development of cardiac dysfunction in the absence of coronary artery disease in diabetes mellitus. This review discusses the latest findings in diabetic humans and in animal models and reviews emerging new mechanisms that may be involved in the development and progression of cardiac dysfunction in diabetes.This publication has 102 references indexed in Scilit:
- Cardiovascular oxidative stress is reduced by an ACE inhibitor in a rat model of streptozotocin-induced diabetesLife Sciences, 2006
- Flow Mediated Dilatation and Cardiac Function in Type 1 Diabetes MellitusThe American Journal of Cardiology, 2006
- Noninvasive Characterization of Myocardial Blood Flow in Diabetic, Hypertensive, and Diabetic–Hypertensive Rats Using Spin‐Labeling MRIMicrocirculation, 2005
- Evidence for mitochondrial thioesterase 1 as a peroxisome proliferator-activated receptor-α-regulated gene in cardiac and skeletal muscleAmerican Journal of Physiology-Endocrinology and Metabolism, 2004
- Streptozotocin directly impairs cardiac contractile function in isolated ventricular myocytes via a p38 map kinase-dependent oxidative stress mechanismBiochemical and Biophysical Research Communications, 2004
- Lipid peroxidation and activity of antioxidant enzymes in diabetic ratsMolecular and Cellular Biochemistry, 1995
- Echocardiographic evidence for the existence of a distinct diabetic cardiomyopathy (The Framingham Heart Study)The American Journal of Cardiology, 1991
- Diabetic cardiomyopathyAmerican Heart Journal, 1989
- Mitochondrial creatine phosphokinase deficiency in diabetic rat heartBiochemical and Biophysical Research Communications, 1988
- New type of cardiomyopathy associated with diabetic glomerulosclerosisThe American Journal of Cardiology, 1972