Inhibiting angiotensin receptors in the brain: possible therapeutic implications
- 1 January 2003
- journal article
- review article
- Published by Informa Healthcare in Current Medical Research and Opinion
- Vol. 19 (5), 449-451
- https://doi.org/10.1185/030079903125001974
Abstract
Arterial hypertension is closely correlated with the occurrence of stroke and also with the loss of cognitive function and dementia. The results of several trials, including Syst-Eur, PROGRESS, and the preliminary findings from SCOPE open the way to the possible prevention of dementia by antihypertensive treatment. In this respect, candesartan seems to be a promising drug as it has been shown to have neuroprotective effects in animal models of cerebral ischaemia and can prevent non-fatal strokes in elderly subjects with arterial hypertension.Keywords
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