Prioritization of disease microRNAs through a human phenome-microRNAome network
Open Access
- 28 May 2010
- journal article
- Published by Springer Science and Business Media LLC in BMC Systems Biology
- Vol. 4 (S1), S2
- https://doi.org/10.1186/1752-0509-4-s1-s2
Abstract
The identification of disease-related microRNAs is vital for understanding the pathogenesis of diseases at the molecular level, and is critical for designing specific molecular tools for diagnosis, treatment and prevention. Experimental identification of disease-related microRNAs poses considerable difficulties. Computational analysis of microRNA-disease associations is an important complementary means for prioritizing microRNAs for further experimental examination.Keywords
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