Enantioselective catalysis and complexity generation from allenoates
Top Cited Papers
- 24 July 2009
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Chemical Society Reviews
- Vol. 38 (11), 3102-3116
- https://doi.org/10.1039/b816700c
Abstract
Lewis base catalysis of reactions with allenoates using phosphine and amine nucleophiles has emerged as a key platform for the generation of molecular complexity. Investigations in this area have established a range of suitable coupling partners for allenoates, including electron-deficient olefins, imines, and aldehydes. This tutorial review will describe these methodologies, with a special emphasis on recent work regarding asymmetric reactions using chiral Lewis base catalysts.Keywords
This publication has 66 references indexed in Scilit:
- Enantioselective Synthesis of Chiral Allenoates by Guanidine-Catalyzed Isomerization of 3-AlkynoatesJournal of the American Chemical Society, 2009
- Phosphine-triggered synthesis of functionalized cyclic compoundsChemical Society Reviews, 2008
- Lewis Base Catalysis in Organic SynthesisAngewandte Chemie-International Edition, 2008
- Nucleophilic Phosphine OrganocatalysisAdvanced Synthesis & Catalysis, 2004
- Asymmetric Organic Catalysis with Modified Cinchona AlkaloidsAccounts of Chemical Research, 2004
- Nucleophilic Chiral Amines as Catalysts in Asymmetric SynthesisChemical Reviews, 2003
- The Simplest "Enzyme"Science, 2002
- Reactions of Electron-Deficient Alkynes and Allenes under Phosphine CatalysisAccounts of Chemical Research, 2001
- Target-Oriented and Diversity-Oriented Organic Synthesis in Drug DiscoveryScience, 2000
- a-ALLENIC ESTERS FROM a-PHOSPHORANYLIDENE ESTERS AND ACID CHLORIDES: ETHYL 2,3-PENTADIENOATEOrganic Syntheses, 1984